Teaching the Machine: How People Teach Algorithms to Replace People

Automation of work via artificial intelligence is becoming a significant issue for societies. This ethnographic study presents a case study that details the process that takes place in order to teach the algorithms that will eventually replace the need for human effort. The author was employed as a data quality analyst and a part of a process where algorithms were taught to generate better content and eventually replace human content creators. The study proposes a three-stage process of automation where the relationship between the humans and algorithms progresses from symbiotic to cannibalistic: the first phase is the commencement phase, where the human employees and algorithms live in symbiosis, reliant on each other. The symbiosis is followed by the expansion phase, where more work is delegated to the algorithms, and the final phase is the automaton phase, where human employees are no longer needed

DEVELOPING AN ONTOLOGICAL VIEW OF OUTSOURCING

An understanding of information technology outsourcing risks, risk categories and their relationships, has been developed over the years from multiple research and theoretical perspectives. These perspectives are not well integrated, however, and do little to develop a common and shared understanding of sourcing risks for organisations. This means that IT sourcing decisions are not well supported by a coherent and well-understood body of knowledge. To start to address the shortcoming, we have conducted three workshops with skilled practitioners and academics to supplement our current understanding of sourcing risk, risk categories and their relationships. From these workshops we have developed an integrated ontological view of sourcing risk which defines the relationships between sixteen risk categories and over hundred and fifty risks, and maps the relationships between them. To facilitate this integrated ontological view we have applied the commonly using OWL and the Protégé-tool to our workshop data.

The Multidimensionality of IT Outsourcing Risks

IT outsourcing is a complex endeavour with multiple sources of risks. The body of knowledge on the subject is vast but scattered. Our project aims to create an integrated risk and controls framework. This paper discusses the multidimensional nature of outsourcing risks that needs to be addressed when such framework is developed. This paper presents findings from two workshops where risks, their classifications and dimensions where discussed by a group of experienced risk practitioners. The results highlight that practitioners see strategy, stakeholders and the different phases of the outsourcing as important dimensions that create risk and needs to be addressed by organisations that are planning or already running an outsourcing venture. This research confirms that there are a number of dimensions in IT outsourcing risk and it has provided depth to the understanding of these dimensions

Agile Software Development: Exploring the Values and Principles, Collaboration and Boundary Objects

Agile software development, both a movement and a set of software development methods, guided by the values and principles state in the Manifesto for Agile development (Beck et al. 2001), should not be seen only as a collection of development methods. This thesis proposes that in order to understand what constitutes differences or similarities between Agile organisations, one should apply a holistic view of Agile development. This view consists of three elements that form the Agile development environment: the perspective the organisations have towards Agile, the Agile process the organisations follow and the Agile structures that form the basis for the process. By proposing this framework of Agile engagement, the thesis answers following research questions: 1. How does collaboration in organisations differ under the various approaches towards Agile? 2. How do organisations structure collaboration between Agile teams and business stakeholders? 3. How are boundary objects used in collaboration between these groups? As research method, I followed the eight steps of the SPS approach and conducted a qualitative, interpretive case study. The study consists of three case studies. First, the Extreme Inc. case is an example of an organisation where the members hold an Avid perspective towards Agile methods. The organisation had arranged the collaboration to follow a tightly integrated model where boundary objects are applied to support the pair programming method and foster face-to-face collaboration. The case of Escapade and Carmine presents an example of an Inclusive Agile perspective, where organisations strive to focus on collaboration and boundary mitigation. The organisations had set up a collaboration configuration, where boundary spanners and all boundary objects were designed to create a sense of presence and ease of collaboration. The last case, the PrecautionCorp program, is a study of an organisation where the members of the organisation have chosen to observe Agile methods in a Pragmatic way. All collaboration between the stakeholders was organised via selected boundary spanners who mitigated the boundaries but also maintained a level of control over the chaos by applying a variety of boundary objects. By analysing the three case studies, I have identified three main elements that impact Agile software development: the perspective the organisations have towards the Agile philosophy which impacts the Agile process, that is, how the Agile methods are applied in practice; the configuration of the business stakeholder collaboration; and the application of the boundary objects. Based on this analysis, I have presented the framework for Agile engagement, a holistic theory that tied together the elements of Agile development. The practical contributions of this thesis are several: practitioners can apply the framework for Agile engagement when analysing their own positions, can benefit from better understanding of the relations between Agile process, Agile perspective and Agile structures, and can enhance their understanding of the best possible application of boundary objects

The Multidimensionality of IT Outsourcing Risks

Abstract: IT outsourcing is a complex endeavour with multiple sources of risks. The body of knowledge on the subject is vast but scattered. Our project aims to create an integrated risk and controls framework. This paper discusses the multidimensional nature of outsourcing risks that needs to be addressed when such framework is developed. This paper presents findings from two workshops where risks, their classifications and dimensions where discussed by a group of experienced risk practitioners. The results highlight that practitioners see strategy, stakeholders and the different phases of the outsourcing as important dimensions that create risk and need to be addressed when organisations are planning or running an outsourcing venture. This research confirms that there are a number of dimensions in IT outsourcing risk and it has provided depth to the understanding of these dimensions

Occupational exposure to metals and other elements in the tractor production

Backgroun

Practical considerations for in vivo MRI with higher dimensional spatial encoding

Object: This work seeks to examine practical aspects of in vivo imaging when spatial encoding is performed with three or more encoding channels for a 2D image. Materials and methods: The recently developed 4-Dimensional Radial In/Out (4D-RIO) trajectory is compared in simulations to an alternative higher-order encoding scheme referred to as O-space imaging. Direct comparison of local k-space representations leads to the proposal of a modification to the O-space imaging trajectory based on a scheme of prephasing to improve the reconstructed image quality. Data were collected using a 4D-RIO acquisition in vivo in the human brain and several image reconstructions were compared, exploiting the property that the dense encoding matrix, after a 1D or 2D Fourier transform, can be approximated by a sparse matrix by discarding entries below a chosen magnitude. Results: The proposed prephasing scheme for the O-space trajectory shows a marked improvement in quality in the simulated image reconstruction. In experiments, 4D-RIO data acquired in vivo in the human brain can be reconstructed to a reasonable quality using only 5% of the encoding matrix—massively reducing computer memory requirements for a practical reconstruction. Conclusion: Trajectory design and reconstruction techniques such as these may prove especially useful when extending generalized higher-order encoding methods to 3D image

Effect of nanosecond repetitive pulsed microwave exposure on proliferation of bone marrow cells

The purpose was to study the proliferative activity of bone marrow mononuclear cells (BMNCs) of rats after irradiated by nanosecond repetitive pulsed microwave (RPM). It was found that the irradiated by nanosecond microwave pulses can affect the BMNCs proliferation in vitro. It is important that both stimulation and inhibition of proliferation were observed after exposure. The effect depended on the pulse repetition frequency. The amount of BMNCs increased after exposure to pulse repetition frequency of 13 Hz up to 30% in comparison with a control cells and up to 51% in comparison with a falseirradiated cells. In contrast, there was inhibition up to 40% of BMNCs after exposure to a frequency of 8 Hz, in comparison with a control group

Charting Coordination Needs in Large-Scale Agile Organisations with Boundary Objects and Methodological Islands

Large-scale system development companies are increasingly adopting agile methods. While this adoption may improve lead-times, such companies need to balance two trade-offs: (i) the need to have a uniform, consistent development method on system level with the need for specialised methods for teams in different disciplines (e.g., hardware, software, mechanics, sales, support); (ii) the need for comprehensive documentation on system level with the need to have lightweight documentation enabling iterative and agile work. With specialised methods for teams, isolated teams work within larger ecosystems of plan-driven culture, i.e., teams become agile “islands”. At the boundaries, these teams share knowledge which needs to be managed well for a correct system to be developed. While it is useful to support diverse and specialised methods, it is important to understand which islands are repeatedly encountered, the reasons or factors triggering their existence, and how best to handle coordination between them. Based on a multiple case study, this work presents a catalogue of islands and the boundary objects between them. We believe this work will be beneficial to practitioners aiming to understand their ecosystems and researchers addressing communication and coordination challenges in large-scale development

WATER-SOLUBLE POLYMERIC IONIC 5-FLUOROURACIL COMPLEX BASED ON METHACRYLIC ACID COPOLYMERS

Objective: The objective of this work was to obtain a water-soluble 5-fluorouracil (5-FU) polymeric complex on the basis of a methacrylic acid (MAA) copolymer to be used as an injectable chemotherapeutic agent. Methods: A polymeric carrier was synthesized using tert-butyl methacrylate (TBMA) as a monomer, thioglycolic acid, and azobisisobutyronitrile as a radical polymerization initiator. The polymer was converted by acid hydrolysis into a water-soluble copolymer of TBMA and MAA of 20: 80 mass%, respectively. The copolymer of TBMA and MAA was modified with 5-FU. Their formation was proved using IR and UV spectroscopy. The particle size of the 5-FU polymeric complex was estimated by turbidimetry, which is based on measuring the intensity of light transmitted through a disperse system. The release of 5-FU from the obtained ionic complexes by dialysis in vitro was evaluated. Results: Polymeric carriers were obtained with different amounts of 5-FU (5, 15, 25, 50 mol%). A high peak at λ = 266 nm was observed in the UV spectrum of the polymeric carrier (characteristic of 5-FU). The particle size was estimated at 13 nm for the complex with 5 mol% 5-FU and 26.8 n for the complex with 50 mol% 5-FU. The 5-FU release was estimated in two parallel experiments at 37 °C. One utilized a phosphate-citrate buffer with pH 5.0 to model the intracellular space and the other, a phosphate buffer with pH 7.4 to model the intravascular space. Two systems, with 5 and 15 mol% 5-FU, were chosen for testing. In both phosphate buffer and phosphate-citrate buffer, 5-FU was released from the polymeric complex with 5 mol% 5-FU approximately 1.3 times faster than from the complex containing 5 mol% 5-fluorouracil. The kinetics of 5-FU release from the polymeric complex (5 mol% 5-fluorouracil) showed that the 5-FU release was 77.9% in phosphate-citrate buffer and 59.6% in phosphate buffer over 52 h of dialysis. When the 5-FU release kinetics was studied with the polymeric complex containing 15 mol% 5-FU, the 5-FU release was 100.0% in phosphate-citrate buffer and 75.1% in phosphate buffer over 57 h of dialysis. Conclusion: Water-soluble nanoscale complexes of 5-FU with TBMA–MAA copolymers extend application of 5-FU, while its general toxicity might be lower. The complexes are sufficiently stable at pH 7.4 and readily release 5-FU at pH 5.0